This could cause the body to have too much strontium and potentially cause side effects. Cottage cheese, 1% milk fat, 1 cup 138 mg per serving. Clin Nucl Med 2004;29:81-5. Interested in more discussions like this? The American Bone Health Fracture Risk Calculator estimates fracture risk for women and men over age 45. Meanwhile, strontium citrate features a 31% elemental strontium and only 69% citrate. Rabenda, V. and Reginster, J. Y. Rheumatol.Int. Ter.Arkh. It's not known if strontium. In the mean time I do have bone density scans to keep an eye on bone density. BMC.Musculoskelet.Disord. The most common supplement form is strontium citrate. Cochrane Database Syst Rev 2006;(4):CD005326. After a 7-day . Most people who take strontium citrate report their fractures STOP. Symptomatic efficacy of avocado/soybean unsaponifiables in the treatment of osteoarthritis of the knee and hip: a prospective, randomized, double-blind, placebo-controlled, multicenter clinical trial with a six-month treatment period and a two-month followup demonstrating a persistent effect. Available at: www.emea.eu.int/humandocs/Humans/EPAR/protelos/protelos.htm. I am fortunate to have no noticeable side effects. J Bone Miner Res 2001;16:299-308. . It can be found in soil and seawater as well as some foods. Hip Intervention Program Study Group. View abstract. Mazor, Z., Brayer, L., Friedman, M., and Steinberg, D. Topical varnish containing strontium in a sustained-release device as treatment for dentin hypersensitivity. Nephrol.Dial.Transplant. Monitoring bone strontium intake in osteoporotic females self-supplementing with strontium citrate with a novel in-vivo X-ray fluorescence based diagnostic tool. Go to the Bones, Joints & Muscles Support Group. Strontium ranelate is available as a prescription medication in Europe and Australia, but it has not been approved by the FDA in the United Sates. 11 possible benefits. In your diet, you get it mainly from seafood, but you can also get small amounts of it in whole milk, wheat bran, meat, poultry, and root vegetables. Interaction of strontium and vitamin D. C R Seances Soc Biol Fil 1975;169:322-9. Thromb.Haemost. Clin Chem 2000;46:248-51. View abstract. (6), Strontium ranelate is a form that is sold as a prescription medication for osteoporosis and bone fractures in Europe and Australia. Its not an idea that is super-new either. Rizzoli, R., Laroche, M., Krieg, M. A., Frieling, I., Thomas, T., Delmas, P., and Felsenberg, D. Strontium ranelate and alendronate have differing effects on distal tibia bone microstructure in women with osteoporosis. View abstract. J.Bone Miner.Res. My bone density has shown some improvement and no further decline. Also, the FDA doesnt regulate supplements in the same way as prescription drugs, so it's not possible to know if if they are safe or work well or even how much of the main ingredient they contain. View abstract. This information may not fit your specific health circumstances. Is it even safe? Lets take a look at the possible health benefits of strontium. I did find some information on the Mayo Clinic website on osteoporosis. Environ Sci Pollut Res Int 2021;28(18):23048-23059. (20). 12-15-2007;57(8):1410-1418. Strontium absorption also has effects on the absorption ofcalcium, magnesium and phosphate ions. View abstract. Bone mass and markers of bone and calcium metabolism in postmenopausal women treated with 1,25-dihydroxyvitamin D (Calcitrol) for four years. Various tests for tooth sensitivity by the researchers revealed that compared to the placebo, the toothpaste containing Sr decreased dentinal hypersensitivity to a significantly greater degree. Positive results were seen within two weeks and continued for the 12 week length of the study. Strontium and calcium metabolism. Due to mixed research findings, its very important to speak with your doctor before supplementing with strontium to treat any health concern especially if you have Pagets disease of bone, kidney problems or any blood clotting disorders. Johnson, G. H., Bales, D. J., Gordon, G. E., and Powell, L. V. Clinical performance of posterior composite resin restorations. In 2013, the committee of the European Medicines Agency (similar to the FDA in the United States) recommended suspending strontium ranelate (brand name Protelos/Osseor) for treating osteoporosis. J.Clin.Endocrinol.Metab 2007;92(8):3076-3081. 2008;39(4):321-325. Strontium as a marker for intestinal calcium absorption: the stimulatory effect of calcitriol. Strontium-89 chloride in the treatment of bone metastases from breast cancer. Glucosamine therapy for treating osteoarthritis. The product can increase bone density, and it can also slow down bone loss. Toxicological profile for strontium. [No authors listed]. Papoiu AD, Valdes-Rodriguez R, Nattkemper LA, Chan YH, Hahn GS, Yosipovitch G. A novel topical formulation containing strontium chloride significantly reduces the intensity and duration of cowhage-induced itch. It's derived from rock calcium bound with citric acid (think citrus juices, especially lime and lemon). What you need to know about strontium suppements for osteoporosis. I have osteoporosis and am afraid of the treatments for it have been trying strontium citrate not sure about my decision. Because strontium ranelate is a weak anti-resorptive agent and there are more effective osteoporosis agents in the United States and most countries, we do not use strontium ranelate in postmenopausal women with osteoporosis. Peng H, Yao F, Xiong S, Wu Z, Niu G, Lu T. Strontium in public drinking water and associated public health risks in Chinese cities. 2013 Feb;98(2):592-601. doi: 10.1210/jc.2012-3048. Bruyere, O., Burlet, N., Delmas, P. D., Rizzoli, R., Cooper, C., and Reginster, J. Y. No tummy upset this time, have been increasing very slowly as I am very med sensitive, so was on 40mg for 10 days and now 40mg one day and 80 mg every second day for a week, but the tiredness is difficult to put up with. AlgaeCal Plus is a plant-based calcium supplement that contains all 13 bone-supporting minerals and is clinically supported to increase bone density. N Engl J Med 2004;350:504-6. 2007;5(4):692-699. With strict editorial sourcing guidelines, we only link to academic research institutions, reputable media sites and, when research is available, medically peer-reviewed studies. A prescription form of strontiumstrontium ranelate (the ranelate salt), known as Protelos/Osseor was authorized in the European Union to treat severe osteoporosis in women who have been through the menopause and men who are at high risk of broken bones or fracture in the spine and the hip. View abstract. Some. Next year will be my third year off the reclast so it will be interesting to see what docs will then suggest. Dahl SG, Allain P, Marie PJ, et al. Note that the numbers in parentheses (1, 2, etc.) Marquis, P., Roux, C., de la Loge, C., Diaz-Curiel, M., Cormier, C., Isaia, G., Badurski, J., Wark, J., and Meunier, P. J. Strontium ranelate prevents quality of life impairment in post-menopausal women with established vertebral osteoporosis. The disease often progresses without any symptoms or pain, and is not found until bones fracture. The possible risks of strontium warrant more long-term independent studies. Rev Rhum Engl Ed 1997;64(12):825-834. A typical dosage of strontium in over-the-counter supplements is 680 mg a day. Its also not for people who: National Osteoporosis Foundation Clinical Updates: "Over-the-Counter Products & Osteoporosis: Case Discussions. View abstract. J.Periodontol. European Medicines Agency, 2005. Arch.Intern.Med. Calcium and strontium metabolic studies in patients on CAPD. Calcium is still the best mineral for bone health. N.Engl.J.Med. View abstract. Its also referred to as being a soft metal like lead. D'Haese PC, Couttenye MM, Lamberts LV, et al. The compound Strontium Citrate has CAS number 40182-75- and molecular formula C6H5O7Sr-. If side effects are persistent or worsen, it is best to talk to your healthcare provider. Strontium ranelate may cause unwanted side effects such as stomach pain, diarrhea and headache. View abstract. 1998;4(2):114-119. Omdahl JL, DeLuca HF. Scaglione M, Fabbri L, Casella F, Guido G. Strontium ranelate as an adjuvant for fracture healing: clinical, radiological, and ultrasound findings in a randomized controlled study on wrist fractures. According to the Michigan Health website: Compared with children with fewer cavities, enamel samples from children with high numbers of caries have been found to contain significantly less strontium. 9-25-2006;166(17):1899-1906. I was told by the endocrinologist who I went to for osteoporosis that AlgaeCal is no better than taking calcium and vitamin D. I am reading the book "Strong Women, Strong Bones" and I highly recommend it. View abstract. Ozgur S, Sumer H, Kocoglu G. Rickets and soil strontium. Research shows that a special prescription form of strontium (strontium-89 chloride) given intravenously (by IV) reduces pain from metastatic, Weak and brittle bones (osteoporosis). Strontium is a mineral found in seawater and soil. 2015 Feb;74(2):422-9. doi: 10.1136/annrheumdis-2013-203989. Its a fancy word for the development of cavities! 1990;1(1):19-23. 1991;13(3):21-25. 2008;58(6):1687-1695. This is more important for postmenopausal women. Pennington JA, Jones JW. 5 Reasons to Add Lamb Meat to Your Diet. 4-12-2005;172(8):1039-1043. In osteoporotic women treated with strontium ranelate, strontium is located in bone formed during treatment with a maintained degree of mineralization. Effects of strontium ranelate on spinal osteoarthritis progression. If youre not into chemistry, then those scientific facts probably dont mean that much to you. Strontium ranelate has risks though. B., Eriksen, E. F., Ish-Shalom, S., Genant, H. K., Wang, O., and Mitlak, B. H. Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis. Strontium is an element that has been shown to improve bone healing. Ardissino G, Schmitt CP, Bianchi ML, et al. J Am Diet Assoc 1987;87:1644-50. 2008;80(5):47-52. A., Mohr, D. N., Petterson, T. M., O'Fallon, W. M., and Melton, L. J., III. Calcium is important for bone health throughout your life. FDA. Liberman, U. Calcium citrate is another of the more common calcium types used in calcium supplements. Strontium Citrate is one of the most common types of Strontium used in the dietary supplement field for bone health. An extensive scientific review published in 2000 concludes that: It is clear from published reports and from daily practice that injection with Sr-89 is a simple, well-tolerated treatment providing a considerable chance of good palliation of pain in patients with bone metastases from prostate cancer. Some research shows that taking strontium ranelate helps prevent. This decreases the amount of quinolones that can be absorbed. Agency for Toxic Substances and Disease Registry. Stable strontiums atomic symbol is Sr, its atomic number is 38 and its atomic weight is 87.62. Rintelen, B., Neumann, K., and Leeb, B. F. A meta-analysis of controlled clinical studies with diacerein in the treatment of osteoarthritis. https://www.mayoclinic.org/diseases-conditions/osteoporosis/in-depth/osteoporosis-treatment/art-20046869, https://connect.mayoclinic.org/discussion/reclast-infusion/, https://americanbonehealth.org/bonesense/why-strontium-is-not-good-for-bone-health/. 1998-2023 Mayo Foundation for Medical Education and Research. Ettinger, B., Black, D. M., Mitlak, B. H., Knickerbocker, R. K., Nickelsen, T., Genant, H. K., Christiansen, C., Delmas, P. D., Zanchetta, J. R., Stakkestad, J., Gluer, C. C., Krueger, K., Cohen, F. J., Eckert, S., Ensrud, K. E., Avioli, L. V., Lips, P., and Cummings, S. R. Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. Founded in 1999, ConsumerLab.com is a leading provider of consumer information and independent evaluations of products that affect health and nutrition. IT was a 9 year nightmare until I started the strontium citrate. 5 Possible (and Controversial) Health Benefits, The Foods, Supplements & Oils to Increase Bone Healing, Daniel Fast: Benefits for Your Spiritual, Emotional and Physical Health, 15 Fermented Foods for a Healthy Gut and Overall Health, 9 Proven Black Seed Oil Benefits that Boost Your Health, L-Glutamine Benefits Leaky Gut & Metabolism, Chia Seeds Benefits: The Omega-3, Protein-Packed Superfood, Apple Cider Vinegar Benefits for Weight Loss, Skin Health, Cholesterol & More. Can Med Assoc J 1981;125:703-12.. View abstract. New treatment strategies: ipriflavone, strontium, vitamin D metabolites and analogs. Z. They. (21). A meta-analysis of chondroitin sulfate in the treatment of osteoarthritis. Osteoporos.Int. (5a). Sr-89 has been used as a form of treatment to manage pain resulting from bone pain due to cancer. Meta-analysis: chondroitin for osteoarthritis of the knee or hip. That means it may affect how strong your bones are. Gillam, D. G., Bulman, J. S., Jackson, R. J., and Newman, H. N. Comparison of 2 desensitizing dentifrices with a commercially available fluoride dentifrice in alleviating cervical dentine sensitivity. Oger, E. Incidence of venous thromboembolism: a community-based study in Western France. View abstract. The application of Sr-89 is cost-effective, especially when compared with [opioid painkillers]. (16), Strontiums name comes from Strontian, a village in Scotland. A., Weiss, S. R., Broll, J., Minne, H. W., Quan, H., Bell, N. H., Rodriguez-Portales, J., Downs, R. W., Jr., Dequeker, J., and Favus, M. Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis. View abstract. Any use of this site constitutes your agreement to the Terms of Use and Privacy Policy and Conditions of Use linked below. Most calcium supplements are big and difficult to swallow. It is also among the forms of Strontium supplements backed by studies regarding safety and efficiency. The body needs zinc for the immune system to work properly. Strontium biokinetics in humans: influence of alginate on the uptake of ingested strontium. Reginster, J. Y. 2004;19(8):1241-1249. This technology we use to assemble our list depends on a variety of factors, including but not limited to the following: Brand Value: Every brand of strontium citrate . I now take 680 mg strontium citrate without side effects and the fractures have stopped. Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. Spets-Happonen, S., Seppa, L., Korhonen, A., and Alakuijala, P. Accumulation of strontium and fluoride in approximal dental plaque and changes in plaque microflora after rinsing with chlorhexidine-fluoride-strontium solution. J.Periodontol. Oral Dis. Strontium Ranelate returns to the UK as an osteoporosis drug treatment. 2019, As a service to our readers, American Bone Health provides access to our library of archived content. View abstract. A., Christiansen, S. C., Romundstad, P., Cannegieter, S. C., Rosendaal, F. R., and Hammerstrom, J. 2004;86-A(3):538-545. The objective of this study was to determine whether strontium citrate can be used to enhance bone healing during MDO in a rabbit model. N.Engl.J.Med. View abstract. Since strontium is denser than calcium, it is difficult to assess actual bone improvement in a DXA scan. It has been licensed for sale in the UK and elsewhere in Europe for treatment of osteoporosis in postmenopausal women. I just read this article about strontium. View abstract. Glucosamine and chondroitin for treatment of osteoarthritis: a systematic quality assessment and meta-analysis. Osteoporos.Int. Periodontics. My Dr wants me to start taking this. 23(1):305-315. doi: 10.1007/s00198-011-1758-z. J Periodontol. Blotman, F., Maheu, E., Wulwik, A., Caspard, H., and Lopez, A. Efficacy and safety of avocado/soybean unsaponifiables in the treatment of symptomatic osteoarthritis of the knee and hip. Kidney Int 2000;58:981-8. Fidelix, T. S., Soares, B. G., and Trevisani, V. F. Diacerein for osteoarthritis. A coordinator will follow up to see if Mayo Clinic is right for you. 2010;46(4):1038-1042. doi: 10.1016/j.bone.2009.12.006. Strontium ranelate is a form that is sold as a prescription medication for osteoporosis and bone fractures in Europe and Australia. View abstract. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Cochrane Musculoskeletal Group. Reichenbach S, Sterchi R, Scherer M, et al. 1992;71 Spec No:841-845. Keep in mind that more research is still needed to confirm its benefits and safety for some of these uses. It is a rarecarbonate mineraland one of only a few strontium minerals. View abstract. View abstract. Les Laboratoires Servier, 2006. Roque, I. Figuls, Martinez-Zapata, M. J., Scott-Brown, M., and Alonso-Coello, P. Radioisotopes for metastatic bone pain. To avoid this interaction, take strontium at least 2 hours before or after taking quinolones. Strontium is similar to calcium. Dose-dependent effects of strontium on osteoblast function and mineralization. Human biokinetics of strontium--part II: Final data evaluation of intestinal absorption and urinary excretion of strontium in human subjects after stable tracer administration. View abstract. JAMA 10-13-1999;282(14):1344-1352. Please note the date of the last review on all articles. View abstract. J.Dent.Res. It may even cause constipation or digestive discomfort. EPI-GETBP Study Group. A special form of strontium called strontium ranelate can increase bone formation and prevent bone loss when used in postmenopausal women with osteoporosis. Concentrations of trace elements in osteoarthritic knee-joint effusions. Hughes, N., Mason, S., Jeffery, P., Welton, H., Tobin, M., O'Shea, C., and Browne, M. A comparative clinical study investigating the efficacy of a test dentifrice containing 8% strontium acetate and 1040 ppm sodium fluoride versus a marketed control dentifrice containing 8% arginine, calcium carbonate, and 1450 ppm sodium monofluorophosphate in reducing dentinal hypersensitivity. 2005;16(10):1291-1298. It is said to have first been found in the ores of lead mines in Strontian in 1787. are clickable links to medically peer-reviewed studies. View abstract. Scientific studies have shown that Sr may have positive effects on bone diseases like osteoporosis, bone cancer, prostate cancer, tooth sensitivity and tooth decay. View abstract. Initially Forteo was top contender (refrigeration requirement is an issue) until I came across Tymlos (refrigeration being easier to manage is one of several benefits over Forteo). (24, 25). Strontium ranelate has also been linked with a small increase in blood clot risk so it should not be taken by anyone with a blood clotting disorder. Protelos European Public Assessment Report, Scientific Discussion. Cummings, S. R., Black, D. M., Thompson, D. E., Applegate, W. B., Barrett-Connor, E., Musliner, T. A., Palermo, L., Prineas, R., Rubin, S. M., Scott, J. C., Vogt, T., Wallace, R., Yates, A. J., and LaCroix, A. Krachler, M., Domej, W., and Irgolic, K. J. CMAJ. Methods: Custom-made MDO devices were placed on 20 New Zealand White rabbits. You also do not know whether they can seriously harm you. Overall, the review concludes: For patients with castration-resistant prostate cancer suffering from malignant bone pain, treatment with a bone-seeking radiopharmaceutical is a relevant therapeutic option often resulting in significant pain reduction. View abstract. View abstract. Medical studies done on the ingredients have shown conclusively that this product is effective. Bruyre O, Reginster JY, Bellamy N, et al. Mayo docs say it will stay in my system for up to three years. The effect of fluoride and strontium application on dentin: in vivo and in vitro studies. It is an alkaline earth metalmost similar to barium and calcium. Oncology 1998;55:377-81. Effectiveness of desensitizing agents. Over-the-counter dentifrices in the treatment of tooth hypersensitivity. Strontium Ranelate returns to the UK as an osteoporosis drug treatment. 2019https://theros.org.uk/latest-news/2019-01-14-strontium-ranelate-returns-to-the-uk-as-an-osteoporosis-drug-treatment. Calcif Tissue Int 2001;69:121-9. . 2006;55(8):669-675. [RETRACTED]. A comparative clinical study investigating the efficacy of a dentifrice containing 8% strontium acetate and 1040 ppm fluoride in a silica base and a control dentifrice containing 1450 ppm fluoride in a silica base to provide immediate relief of dentin hypersensitivity. I was diagnosed with osteopenia", "I have osteoporosis and am afraid of the treatments for it have been trying strontium citrate", "My wife has severe Osteoporosis .It has been improving with Medicines, Yearly injections , Exercise ,". Bone 2009;45(2):200-206. Severe allergic reactions to magnesium oxide are rare. Feeling slightly more pain in the areas of cancer in your bones for a few days. (19), If youre a fan of red fireworks, you can thank strontium (specificallygaseous strontium monochloride) for that brilliant color you see every 4th of July. Adami, S. Protelos: nonvertebral and hip antifracture efficacy in postmenopausal osteoporosis. Estrogens might decrease how fast the body gets rid of strontium. It does not recommend it as a treatment for anyonewho has or has had heart or circulatory problems such as stroke, heart attack, or obstruction of the blood flow in the arteries. Groupe d'Etude de la Thrombose de Bretagne Occidentale. 2007;18(12):1617-1624. Supplements are increasingly available over the counter and through the Internet. [2] Royal Osteoporosis Society. View abstract. Skoryna SC. Available at: www.servier.com/pro/osteoporose/protelos/protelos_spc.asp. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. Some people say this supplement improves bone health, but its important to think about its benefits and risks before you decide to take it. Effect of risedronate on the risk of hip fracture in elderly women. WebMD does not provide medical advice, diagnosis or treatment. You do not know what amounts your body is getting when you take these supplements. Doctors arent sure exactly how it works, but it seems to help the body make more bone and keep the bone you have from breaking down. A generic, non-branded version of strontium ranelate, from Aristo Pharma Ltd., is still available in the U.K.[2] with a number of special warnings and precautions for its use. Pelletier JP, Roubille C, Raynauld JP, et al. Connect with thousands of patients and caregivers for support, practical information, and answers. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician, https://www.ema.europa.eu/en/news/prac-recommends-suspending-use-protelososseor, https://theros.org.uk/latest-news/2019-01-14-strontium-ranelate-returns-to-the-uk-as-an-osteoporosis-drug-treatment. Disease-modifying effect of strontium ranelate in a subset of patients from the Phase III knee osteoarthritis study SEKOIA using quantitative MRI: reduction in bone marrow lesions protects against cartilage loss. (Accessed 01 August 2006). 1992;63(1):7-12. Barenholdt, O., Kolthoff, N., and Nielsen, S. P. Effect of long-term treatment with strontium ranelate on bone strontium content. Several different forms of strontium are used as medicine and strontium chloride is the most common form of strontium found in. Osteoporos.Int. Osteoporos.Int. They can decrease strontium absorption. What else is it good for? Effects of oral supplementation with stable strontium. However, there has also been concern over strontium ranelates effects on heart health.